ACTIVE HALF-LIFE
24 hours
CLASSIFICATION
Antibiotic / Macrolide Combination, Gastrointestinal Agent / Miscellaneous
DOSAGE
1530 mg/day
ACNE
No
WATER RETENTION
No
HBR
No
HEPATOTOXICITY
Low
AROMATIZATION
No
MANUFACTURER
Deva
WAREHOUSE
International Warehouse 2
SUBSTANCE
Amoxycillin, Clarithromycin, Lansoprazole
Discover the Benefits of Trio
Trio is expertly formulated to effectively treat and prevent gastrointestinal (GI) ulcers caused by infections, offering you a reliable solution for digestive health.
Essential Information to Discuss with Your Healthcare Provider Before Using Trio
- Notify your doctor if you have allergies to lansoprazole, amoxicillin, clarithromycin, any penicillin, or any other components in this medication.
- Share any other allergies you may have, including those to foods, medications, or substances, along with any symptoms experienced, such as rashes, hives, or respiratory issues.
- Inform your healthcare provider if you have a history of liver problems associated with these medications.
- Discuss previous occurrences of prolonged QT intervals or other heart rhythm irregularities.
- Let your doctor know if you have low magnesium or potassium levels, or a slow heartbeat.
- If you have kidney or liver disease and are taking colchicine, please inform your doctor.
- Review any other medications (prescription or over-the-counter), natural supplements, or vitamins you?re taking, especially for high cholesterol, migraines, or mental health conditions that may interact with this treatment.
- Consult your doctor or pharmacist if you are using medications that may cause abnormal heart rhythms (prolonged QT interval).
- Notify your healthcare provider if you are breastfeeding or plan to do so.
Key Considerations While Taking Trio
- Be aware that severe allergic reactions, though rare, can occur. Contact your doctor if you have any concerns.
- Seek medical advice if you experience symptoms like throat or chest pain, severe abdominal discomfort, difficulty swallowing, or signs of a bleeding ulcer, such as black, tarry, or bloody stools.
- Avoid alcohol consumption while on this medication.
- This medication may increase the risk of fractures in individuals with osteoporosis, especially when used in high doses over a year or in patients over 50. Discuss this risk with your doctor.
- Low magnesium levels have been reported in some patients taking Trio long-term. Regular blood tests might be necessary if you are on this medication for an extended period.
- Watch for signs of liver issues, such as dark urine, fatigue, or jaundice, and seek immediate medical attention if they occur.
- Monitor for abnormal heart rhythms, particularly when combined with other medications. Seek help if you notice irregular heartbeats.
- There have been instances of lupus associated with this medication. Inform your doctor if you have lupus and report any related symptoms.
- In rare cases, serious reactions may occur, exhibiting symptoms like fever and rash. Consult your physician about any such issues.
- If you have heart disease, make sure to inform your doctor, as some studies suggest an increased mortality risk with clarithromycin.
- Seniors (65 years and older) should use caution, as they may be more prone to adverse effects.
- This medication may reduce the effectiveness of hormonal birth control. Consider using additional contraceptive methods while on Trio.
- Consult your doctor if you are pregnant or conceive while taking Trio, as risks to the unborn child may arise.
Recommended Administration of Trio
Adhere to your doctor?s instructions when using lansoprazole, amoxicillin, and clarithromycin. Follow all provided information closely for optimal benefits.
- To maximize effectiveness, do not miss doses.
- Continue taking Trio as directed by your healthcare provider, even if you start feeling better.
- Take the medication before meals for best results.
- If you are using sucralfate, take lansoprazole, amoxicillin, and clarithromycin at least 30 minutes before it.
- Inform all your healthcare providers, including doctors and pharmacists, about your use of this medication.
- If you have diabetes, avoid using Clinitest?; consider alternatives like Clinistix? or Tes-Tape?.
- This medication can impact certain lab tests; inform your healthcare and lab personnel accordingly.
- Monitor your blood work as recommended by your physician for proper health management.
- Discuss with your doctor if you are taking other medications, as monitoring may be required for drug interactions.
- Exercise caution if you are at risk for fragile bones (osteoporosis) due to lifestyle factors or family history; discuss this with your doctor.

