ACTIVE HALF-LIFE
4-5 hours
CLASSIFICATION
SNRIs & PDE5 inhibitor
DOSAGE
Men 130 mg/day
ACNE
No
WATER RETENTION
No
HBR
Possible
HEPATOTOXICITY
No
AROMATIZATION
No
MANUFACTURER
Sunrise Remedies
WAREHOUSE
International Warehouse 1
SUBSTANCE
Duloxetine, Sildenafil
Introducing Malegra DXT by Sunrise Remedies, a powerful combination of Sildenafil and Duloxetine designed to elevate your sexual experience. Sildenafil is renowned for its ability to effectively treat erectile dysfunction, while Duloxetine helps manage premature ejaculation, creating a comprehensive solution for men seeking improved intimacy. Although Malegra DXT is typically a prescription medication, it is conveniently available online without a prescription. However, we strongly recommend consulting with your healthcare provider before use, especially if you are on other medications due to potential side effects. Malegra DXT is offered exclusively in an easy-to-swallow oral capsule form.
How It Works:
Malegra DXT works by enhancing the natural sexual response. When aroused, nitric oxide is released, crucial for achieving and maintaining an erection. This process activates guanylate cyclase, increasing levels of cGMP (cyclic guanosine monophosphate) that relaxes smooth muscle in the corpus cavernosum, allowing increased blood flow to the penis. Sildenafil further amplifies this effect by inhibiting PDE5 (Phosphodiesterase type 5), which would otherwise reduce cGMP levels. Remember, Sildenafil requires sexual stimulation to take effect, activating only when nitric oxide is released during arousal. Once ingested, Sildenafil is rapidly absorbed, typically within one hour, and metabolized primarily by cytochrome P450 3A4, leading to an active metabolite.
Duloxetine, a thiophene derivative, acts as a selective serotonin reuptake inhibitor, helping to ease anxiety during sexual activities. By slowing nerve sensations in the glans penis, it extends the duration of intercourse and aids in preventing premature ejaculation.
Dosage:
Malegra DXT is specifically formulated to tackle sexual dysfunction, featuring 100 mg of Sildenafil and 30 mg of Duloxetine. Sildenafil is absorbed by the liver within 30 minutes, promoting increased blood flow in the corpus cavernosum, leading to an erection typically within one hour that can last between 4 to 5 hours. Meanwhile, Duloxetine works on the nerve centers to alleviate performance anxiety, further preventing premature ejaculation.
Malegra DXT is available in two dosages: 75 mg and 130 mg, with the 130 mg option often recommended by physicians for optimal results. It is advised to take one capsule one hour before planned sexual activity, and medical professionals caution against exceeding one dose per day.
Side Effects:
While Malegra DXT is generally safe and effective, some users may experience mild side effects primarily due to blood vessel dilation. Common side effects may include nausea, insomnia, flushing, muscle pain, dyspepsia, dizziness, vomiting, loose stools, epistaxis, and erythema.
Drug Interactions:
Be cautious with Malegra DXT if you are taking alpha blockers, as it may lower blood pressure. Additionally, use of erythromycin or cimetidine may prolong penile erection.